What is the Methylation Pathway?

The methylation pathway illustrates our bodies' ability to detoxify the system. This is how we process heavy metals, making them water-soluble so that we can excrete them through urine.  The markers listed below are called Single Nucleotide Polymorphisms (SNPs), which are mistakes or 'hiccups' in our genes. The presence of these SNPs affect our ability to process through the methylation pathway effectively. We offer two different genetic testing options which will look at your unique genetic makeup and expose which SNPs you present.  Those tests are described below.

It is important to note that while you cannot control your genetic makeup, it is possible to turn your SNPs off with the aid of proper diet and supplementation. 
 

When your genetic results show a heterozygous (one donor) or homozygous (two donors) 'hit' for some of these SNP markers, Dr P is then able to identify which portions of the cycle could be processing too slowly or too quickly. After you have had your specific SNPs identified, we will then order a couple of urine tests which will show which SNPs are currently 'turned on'. This exposes which portions of the pathway are CURRENTLY affecting your ability to detoxify. Dr P will then supplement accordingly, helping the pathway to function most effectively.  When the methylation cycle runs smoothly, energy levels will increase, brain fog will clear, and sleep quality will improve. 
 

What happens when your body is not methylating effectively?

• You may accumulate abnormal levels of toxic heavy metals. These heavy metals are found in food, vaccinations, and the environment. As we mentioned earlier, the methylation cycle is how the body processes these metals and excretes them through urine. 
• You may gradually develop signs of cardiovascular disease such as abnormal blood pressure, enlarged heart, orthostatic intolerance, chest pain or postural orthostatic tachycardia syndrome. However, many people have no indication of problems at all until they suffer a heart attack.
• You may have blood which clots rapidly, and therefore develop thromboses or strokes.
• You may suffer memory impairment and may have a range of other neurological problems.
• Some children on the autism spectrum have been found to have brain abnormalities which may derive from inadequate methylation of nerve cells during critical stages of brain development in early childhood. Folic acid (in the correct form) is essential for methylation, and lack of folic acid in pregnant women has long been known to result in brain and spinal abnormalities such as spina bifida. After birth, this methylation process continues to be vital in the development of baby and toddler brains.
• You may be at increased risk of cancer.
• You may be susceptible to a wide range of chronic inflammatory illnesses, including some autoimmune conditions. This is derived from inadequate methylation of monocytes and lymphocytes. A link has been established between under-methylation of these cells and the development of autoimmune diabetes and systemic lupus erythematosis.
• You will possibly have a weakened immune system and be unable to sustain a strong immune defense against infections.